• Indicated in…… • Acne Vulgaris • Very effective for acne in both dry and oily skin.
• Mechanism of action… Clindamycin • Clindamycin has a primarily bacteriostatic effect. It is a bacterial protein synthesis inhibitor by inhibiting ribosomal translocation, in a similar way to macrolides. • Topical clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles. • Mechanism of action… Nicotinamide • Nicotinamide is one of the principle forms of B complex,vit.B3(niacin) with marked anti inflammatory activity.it reduces acne lesions,pustules,papules and acne sensitivity.
